Lumbar Disc Replacement

Speaker notes · 20 min · v1.1 · updated 2026-10-11

  1. A talk for patients and families

    Lumbar Disc Replacement

    Keeping your spine moving: what it is, who it helps, and what the long-term studies show

    Aaron Wey, MD, FAAOS, FACS
    Adult & Pediatric Spine Surgeon
    Literature reviewed through October 2026
    Version 1.1 · Updated 2026-10-11
    1 / 15~1 min · at 0:30
    The basics

    Welcome. This short talk explains what a lumbar disc replacement is, who is a good candidate, and what the research shows about how well it works and how long it lasts. Every number in this talk comes from a published study; the list is on the last slide and the full list with links is on this deck's reference page. Please interrupt with questions at any point.

  2. The basics

    A worn-out disc has two surgical answers

    Worn-out disccollapsed, painfulFusioncage and screws: lockedDisc replacementplates and core: moves

    Both operations remove the painful disc. The difference is what happens to the motion afterwards.

    The basics
    2 / 15~2 min · at 2:00
    The basics

    Both operations start the same way: the painful, worn-out disc is removed. In a fusion the two bones are then joined with a cage, bone graft and screws, and over months they heal into one bone. That stops the pain generator, and it also stops the motion at that level. In a disc replacement an artificial disc goes in its place: two metal plates that grip the bone and a smooth plastic core between them, so the level keeps bending. The operation is done through a small incision in the lower abdomen, with the organs moved aside, which is why a vascular surgeon often helps with the approach.

  3. The basics

    Who it is for, and who it is not for

    A good candidate

    • One worn-out disc between L3 and S1, usually L4-5 or L5-S1, with pain coming from the disc itself
    • Back pain more than leg pain; the disc wear is confirmed on MRI and matches the symptoms
    • At least six months of nonsurgical care that did not work
    • Healthy bone: a bone-density T-score better than minus 1.0
    • Healthy facet joints behind the disc, and no more than a slight slip of the vertebra
    • Age 18 to 60 for most insurers; a fully grown skeleton for the FDA

    Not a candidate

    • Osteoporosis or osteopenia (T-score of minus 1.0 or worse)
    • Worn-out, arthritic facet joints; a stress fracture (pars defect) or a slipped vertebra
    • Spinal stenosis, or nerve pain down the leg as the main problem
    • A previous fusion at that level, or more levels than the device is approved for
    • Scoliosis, infection, or allergy to the metal or plastic in the implant
    • Insurers add: severe obesity, nicotine use, and untreated depression or substance use

    FDA approval labeling for prodisc L and activL; Aetna, Cigna and Carelon medical policies, 2026. FDA 2020 FDA 2015 Aetna 2026 Cigna 2026 Carelon 2026

    The basics
    FDA 2020 · FDA 2015 · Aetna 2026 · Cigna 2026 · +1
    3 / 15~2 min · at 3:40
    The basics

    Selection is what makes this operation work, so here is who it is for and who it is not for. The left column comes from the FDA approval labeling of the two discs on the US market, prodisc L and activL FDA 2020 FDA 2015, plus the insurers. A good candidate has one worn-out disc between L3 and the sacrum, usually L4-5 or L5-S1, with pain that comes from the disc itself: back pain more than leg pain, and MRI wear that matches the symptoms. At least six months of nonsurgical care has been tried. The bone is healthy, which we check with a bone-density scan; a T-score of minus 1.0 or worse rules it out, because the plates have to seat in solid bone. The facet joints behind the disc are healthy, and any slip of the vertebra is slight. Most insurers limit it to ages 18 to 60, the range the trials studied Aetna 2026 Cigna 2026 Carelon 2026.

    Who it is not for: osteoporosis or osteopenia; arthritic facet joints, a stress fracture in the back of the vertebra or a slipped vertebra, because then the pain is not only from the disc and the joint would still move on a damaged hinge; spinal stenosis or leg-dominant nerve pain, which needs a decompression; a previous fusion at that level or more levels than the device is approved for; scoliosis, infection, or allergy to the implant materials. The insurers add severe obesity, nicotine and untreated depression or substance use.

    Park's ten-year study shows why this matters: well-selected patients had 77 percent success and 87 percent satisfaction; poorly selected patients 40 and 60 percent Park 2016.

    Pearl: Selection is the operation. The ten-year results are good in the right patient and poor in the wrong one.
    Refs: FDA, US Food and Drug Administration, 2020 · FDA, US Food and Drug Administration, 2015 · Aetna, Aetna Clinical Policy Bulletins, 2026 · Cigna & EviCore, Cigna Medical Coverage Policies: Musculoskeletal (EviCore), 2026 · Carelon, Carelon Medical Benefits Management, 2026
  4. What the studies show

    Does it work? Yes, as well as fusion

    77%
    of patients satisfied five years after surgery, the same as after fusion, in the largest US trial
    ProDisc-L trial, 5 years Zigler 2012
    82%
    would have the same surgery again, versus 68% of fusion patients
    ProDisc-L trial, 5 years Zigler 2012
    6% vs 12%
    repeat operations with disc replacement versus fusion, pooled from 13 randomized trials
    Meta-analysis, 2,349 patients Patel 2026
    What the studies show
    4 / 15~2 min · at 5:10
    What the studies show

    The first question everyone asks: does it work? Three large randomized trials were run in the United States to get the devices approved, each comparing a disc replacement with a fusion. All three showed that disc replacement relieves pain and improves function at least as well as fusion Blumenthal 2005 Zigler 2007 Garcia 2015. At five years in the ProDisc-L trial, 77 percent of patients in both groups were satisfied, but 82 percent of the replacement patients said they would have the surgery again compared with 68 percent of the fusion patients Zigler 2012. When the randomized trials are pooled, patients with a replacement needed about half as many repeat operations: roughly 6 percent versus 12 percent Patel 2026 Zigler 2018. One honest footnote: a Norwegian trial compared replacement with an intensive rehabilitation program rather than fusion, and at eight years the difference in function was small, although a quarter of the rehabilitation patients ended up choosing surgery Furunes 2017. Surgery is for people who have already given nonsurgical care a real try.

  5. What the studies show

    Why patients choose it

    38%
    completely pain-free at five years, versus 15% after fusion
    Swedish randomized trial Sköld 2013
    66%
    working full-time at five years, versus 47% after fusion
    Charité trial Guyer 2009
    95%
    of athletes back to their sport, most within six months
    39 athletes Siepe 2007
    0%
    still taking opioids at seven years in the activL trial
    283 patients Radcliff 2021
    What the studies show
    5 / 15~2 min · at 6:40
    What the studies show

    These are the numbers that explain why patients who qualify tend to choose a replacement. In the Swedish randomized trial, with 99 percent follow-up at five years, 38 percent of replacement patients said they were completely pain-free, compared with 15 percent after fusion; function scores were better as well Sköld 2013. In the Charité trial, 66 percent of replacement patients were working full-time at five years compared with 47 percent after fusion, and only 8 percent were on long-term disability compared with 21 percent Guyer 2009. In a series of 39 athletes, 95 percent returned to their sport, most within six months, and 85 percent said their performance improved Siepe 2007. In the activL trial, nobody in either replacement group was still taking opioids at seven years Radcliff 2021; across the pooled trials, fewer replacement patients were using narcotics than fusion patients Patel 2026.

    Recovery is also faster: the Swedish trial found replacement patients had reached their best result by one year, while fusion patients took two Berg 2009. And it holds up: at a mean of nearly fourteen years in a Spanish series, 74 percent were still in their original job and no implant had been revised Vanaclocha 2025. For balance, a 17-year workers' compensation series had 81 percent back to work but 38 percent needing some further surgery Carlson 2022.

    Pearl: Replacement patients reached their best result by one year; fusion patients took two. Most of the difference is the motion, and getting it back sooner.
  6. What the studies show

    In the hospital: fewer complications, less blood loss

    7 vs 13%
    any complication in the hospital, replacement versus fusion, after matching patients
    8,049 replacements vs 1.13 million fusions, US database 2010 to 2019 Upfill-Brown 2022
    3 vs 8%
    blood transfusion
    Same database Upfill-Brown 2022
    $4,500
    lower hospital cost, and about two-thirds of a day shorter stay
    Same database Upfill-Brown 2022
    What the studies show
    6 / 15~1 min · at 7:50
    What the studies show

    The hospital side of the story comes from a national database of US admissions between 2010 and 2019: about 8,000 lumbar disc replacements compared with 1.1 million fusions, matched for age, sex and health Upfill-Brown 2022. Any in-hospital complication occurred in 7 percent of replacement patients versus 13 percent of fusion patients; blood transfusion in 3 percent versus 8 percent; the stay was about two-thirds of a day shorter; and the hospital cost was about 4,500 dollars lower. Another analysis using insurance claims found a slightly longer stay for arthroplasty than for one type of anterior fusion, so I would not promise a specific number of days Khalid 2023; what is consistent is fewer complications and less blood loss.

    The reasons are mechanical: no bone has to heal, so there is no brace and no waiting; no screws go through the back muscles; and the front approach spares the muscles that hold you upright. The Swedish economic analysis found the health-care cost of replacement was lower than fusion over two years, with similar overall value Fritzell 2011.

  7. What the studies show

    It keeps the level moving

    6 vs 1°
    bending motion at the operated level five years after replacement versus fusion
    Charité trial, 5 years Guyer 2009
    9 in 10
    operated levels still moving more than ten years later, with about 10° of bend
    106 patients, mean 13 years David 2007
    Normal
    range of motion in 94% of patients at two years, held steady through year five
    ProDisc-L trial Zigler 2007
    Caveat
    over many years some levels slowly stiffen or bridge with bone; in the long-term studies this rarely changed how patients felt
    15-year series Lu 2018
    What the studies show
    7 / 15~2 min · at 9:20
    What the studies show

    This is the reason to choose a replacement over a fusion: the level keeps moving. In the Charité trial, the operated level bent about six degrees at five years after a replacement, compared with about one degree after a fusion Guyer 2009. In the ProDisc-L trial, 94 percent of patients had a normal range of motion at two years and it held steady through year five Zigler 2007 Zigler 2012. The longest series are reassuring: David followed 106 patients for an average of thirteen years and found 9 in 10 levels still moving, with about ten degrees of bend David 2007; Lemaire's hundred patients at ten years showed about the same Lemaire 2005. The honest caveat is that over many years some levels slowly stiffen, and bone can bridge around the implant; in one fifteen-year series that happened in most segments, yet 93 percent of patients still had a good result Lu 2018. Stiffening is common; trouble from it is not.

  8. What the studies show

    How long does it last?

    1 in 80
    implants removed or exchanged over twenty years of use at one high-volume center, 2,141 patients
    Device removal or revision 1.26% Guyer 2024
    15 yrs
    the longest published follow-up: 93% good or excellent results and no device failures in 30 patients
    Charité III, mean 15.2 years Lu 2018
    ~1 in 10
    patients have some further spine surgery within ten years: a fusion added at that level, or surgery at a neighbouring level
    10-year series David 2007
    None
    no 20-year studies yet: the first modern devices date from the late 1980s and published follow-up stops at about 15 years
    What we do not have Lu 2018
    What the studies show
    8 / 15~2 min · at 11:00
    What the studies show

    How long does it last? Two different questions hide in there. The first is whether the implant itself fails. At one center that has done these operations for twenty years, only 1 in 80 implants, 1.3 percent of 2,141 patients, was ever removed or exchanged Guyer 2024. In the longest published follow-up, thirty patients at an average of fifteen years, 93 percent had a good or excellent result and no implant had failed Lu 2018; David's 106 patients at thirteen years were similar David 2007. The second question is whether you might need any further spine surgery. That is more common: across the ten-year studies about 1 in 10 patients had another operation, usually a fusion added at the same level or surgery at a neighbouring level Lemaire 2005 David 2007 Park 2016, and in one Danish series it was one in three Laugesen 2017; a systematic review of studies with at least five years of follow-up put reoperation at about 14 percent Wen 2024. I would rather you hear that from me than from the internet. And what we do not have is twenty-year data. The devices have been in use since the late 1980s, but published follow-up stops at about fifteen years. So I can tell you it has lasted fifteen years in the patients studied; I cannot promise twenty.

    Pearl: Separate two questions: will the implant fail (rare), and might I need any further spine surgery (about 1 in 10 by ten years).
  9. What the studies show

    Does it wear out like a knee replacement?

    Knee replacement

    • 82% still in place at 25 years Evans 2019
    • Carries your full body weight with every step
    • Today's knees fail mostly from loosening or infection, not plastic wear Sharkey 2014

    Disc replacement

    • Same metal-on-plastic bearing idea, under far smaller loads and motion
    • Retrieved implants show small wear: about 0.3 mm after up to 16 years Kurtz 2007
    • Bone loss from wear particles is rare Punt 2012; removal for any reason about 1 in 80 Guyer 2024

    Neither implant is forever, and neither is likely to wear out in a lifetime of normal use. A disc replacement is not immune to wear; it is simply a lightly loaded joint.

    What the studies show
    Evans 2019 · Sharkey 2014 · Kurtz 2007 · Punt 2012 · +1
    9 / 15~1 min · at 12:20
    What the studies show

    Patients who know someone with a knee replacement ask whether this will wear out the same way. A modern knee replacement is a very good operation: 82 percent are still in place at 25 years Evans 2019, and when a knee does fail today it is usually from loosening or infection rather than the plastic wearing through Sharkey 2014. A disc replacement uses the same idea, a metal-on-plastic bearing, but it carries far smaller loads and moves through a much smaller arc than a knee. Studies of implants that were removed for other reasons show measurable but small wear, about a third of a millimetre after up to sixteen years, with some cracking at the rim of older designs Kurtz 2007; bone loss from wear particles has been reported but is rare Punt 2012. So the honest answer is: it is not immune to wear, it is a lightly loaded joint, and at fifteen years of follow-up wear has not been a common reason for removal. Removal for any reason runs about 1 in 80 Guyer 2024.

    Refs: Evans et al., Lancet, 2019 · Sharkey et al., J Arthroplasty, 2014 · Kurtz et al., Spine J, 2007 · Punt et al., Spine (Phila Pa 1976), 2012 · Guyer et al., Spine (Phila Pa 1976), 2024
  10. What the studies show

    Protecting the discs next door

    9% vs 29%
    neighbouring discs showing new wear on X-ray at five years, replacement versus fusion
    ProDisc-L trial Zigler 2012
    2% vs 4.5%
    surgery at a neighbouring level: 1,000 replacement patients versus published fusion rates
    Rainey 2012 Rainey 2012
    4% vs 8%
    adjacent-level disease across 13 randomized trials of replacement versus fusion
    Meta-analysis Patel 2026
    What the studies show
    10 / 15~1 min · at 13:40
    What the studies show

    The second reason to keep motion is the discs next door. When a level is fused, its share of bending moves to the levels above and below, and over the years those discs wear faster. In the ProDisc-L trial, at five years 9 percent of replacement patients had new wear in a neighbouring disc on X-ray compared with 29 percent of fusion patients Zigler 2012. In a thousand replacement patients, 2 percent needed surgery at a neighbouring level, against about 4.5 percent reported after fusion Rainey 2012, and the pooled randomized trials show adjacent-level disease in about 4 percent versus 8 percent Patel 2026; an older systematic review found a similar gap Harrop 2008. I want to be precise here. The X-ray difference is consistent. The difference in actual neighbouring-level operations within a single trial is small, and a Norwegian study found neighbouring discs wore at the same rate as in patients who had no surgery at all Furunes 2018. So: less wear next door is well supported; a lifetime with fewer operations is likely but not yet proven beyond ten years.

  11. Your decision

    Risks, and what recovery looks like

    Risks

    • Approach through the abdomen: injury to a large blood vessel in about 2 in 100 Ahn 2024
    • In men, retrograde ejaculation in up to 1 in 10; usually temporary, sometimes not Lindley 2012
    • Implant settling or shifting, mostly in the first year; a later fusion is possible if the level stays painful
    • The usual risks of any spine surgery: infection, blood clot, nerve irritation

    Recovery, typically

    • Walking the day of surgery; home in one to two nights
    • No brace; no waiting for bone to heal
    • Desk work in two to four weeks; driving when off strong pain medicine
    • Lifting limits for about six weeks, then physical therapy toward full activity by three months
    Your decision
    Ahn 2024 · Lindley 2012
    11 / 15~2 min · at 15:10
    Your decision

    The risks. The operation is done from the front, through the abdomen, which is what makes the recovery quick, but it means the large blood vessels have to be moved aside; injury to one of them happens in about 2 in 100 cases and is why an access surgeon is often part of the team Ahn 2024. In men, the nerves that control ejaculation run across the front of the spine; retrograde ejaculation, where semen flows backward into the bladder, was reported in up to 1 in 10 men in one series, and it is usually but not always temporary Lindley 2012. The implant can settle into the bone or shift, mostly in the first year, and if the level stays painful it can be converted to a fusion later. And the usual risks of any spine surgery apply: infection, blood clots, nerve irritation. Recovery: patients walk the day of surgery and go home in one or two nights; there is no brace and no waiting for bone to heal; desk work in two to four weeks; driving once off strong pain medicine; lifting limits for about six weeks, then therapy toward full activity by three months. Those are typical figures for our practice and I will tailor them to you.

    Refs: Ahn et al., Spine (Phila Pa 1976), 2024 · Lindley et al., Spine (Phila Pa 1976), 2012
  12. Your decision

    What it takes to get it approved

    • Age 18 to 60, one level between L3 and S1, an FDA-approved disc. Aetna, Cigna and Carelon all require it; Original Medicare does not cover it after 60 Aetna 2026 Cigna 2026 Carelon 2026 CMS 2007
    • Six consecutive months of documented nonsurgical care: medication and supervised exercise or physical therapy, with dates; Aetna wants at least three months of in-person therapy within the past year
    • Recent imaging: standing and bending X-rays and an MRI, within six months for Aetna, showing one worn disc and no stenosis, slip over 3 mm, pars defect or scoliosis
    • A bone-density scan with a T-score better than minus 1.0
    • Pain and function scores in the chart: pain at least 5 out of 10 for Aetna, a disability score, and what you can no longer do
    • Health optimised: HbA1c under 8% if diabetic; depression, anxiety and substance use treated; nicotine-free strongly recommended. Horizon reviews these requests through TurningPoint Horizon 2020
    Your decision
    Aetna 2026 · Cigna 2026 · Carelon 2026 · CMS 2007 · +1
    12 / 15~2 min · at 16:40
    Your decision

    Insurers approve this operation, but they check a list, and it helps to know the list before we start. Age 18 to 60, one level between L3 and the sacrum, and an FDA-approved disc: Aetna, Cigna and Carelon all require it Aetna 2026 Cigna 2026 Carelon 2026; UnitedHealthcare covers a single level with its own criteria UnitedHealthcare 2026. Original Medicare does not cover lumbar disc replacement after age 60 at all CMS 2007.

    Six consecutive months of documented nonsurgical care: medication and a supervised exercise program or physical therapy, with the dates; Aetna specifically wants at least three months of in-person physical therapy within the past year, so a home program alone will not satisfy it. Recent imaging: standing and bending X-rays and an MRI, within six months for Aetna, showing a single worn disc and none of the things that rule it out, such as stenosis, a slip over three millimetres, a pars defect or scoliosis. A bone-density scan with a T-score better than minus 1.0; every policy that lists criteria requires it. Pain and function scores in the chart: Aetna wants pain of at least five out of ten, and all of them want a disability score and a description of what you cannot do. And health optimised: a haemoglobin A1c under 8 percent if you are diabetic, depression, anxiety or substance use under treatment, and no nicotine, which Carelon strongly recommends and which matters for healing in any case.

    In New Jersey, Horizon sends these requests to a review company called TurningPoint, whose checklist is similar but not public Horizon 2020. Our office checks your plan before we set a date, and most of these items are things we collect during the months of nonsurgical care, so by the time we decide on surgery the file is ready.

    Pearl: Most of the approval file is built during the six months of nonsurgical care. Keep every therapy note and every date.
    Refs: Aetna, Aetna Clinical Policy Bulletins, 2026 · Cigna & EviCore, Cigna Medical Coverage Policies: Musculoskeletal (EviCore), 2026 · Carelon, Carelon Medical Benefits Management, 2026 · CMS, Medicare Coverage Database, 2007 · Horizon, Horizon Blue Cross Blue Shield of New Jersey, 2020
  13. Your decision

    Next steps, and the question of insurance

    • Confirm you are a candidate: a recent MRI, standing and bending X-rays, and sometimes a CT or bone-density scan
    • Finish the nonsurgical trial: six documented months of therapy, medication and, when appropriate, injections
    • Check coverage early. Most commercial plans cover a single-level replacement when the checklist on the previous slide is met; Original Medicare does not cover it after age 60 CMS 2007
    • Decide together: replacement, fusion, or more time without surgery. Our team walks you through the authorization and the schedule
    Your decision
    CMS 2007
    13 / 15~1 min · at 17:50
    Your decision

    Where we go from here. First we confirm you are a candidate: a recent MRI, standing and bending X-rays, and sometimes a CT scan or a bone-density test, to look at the disc, the facet joints, stability and bone quality. Second, the nonsurgical trial has to be finished and documented: six months of therapy, medication and, when appropriate, injections, because it is good medicine and because every insurer asks for it. Third, coverage. Most commercial plans cover a single-level disc replacement when the criteria are met. Original Medicare, however, does not cover lumbar disc replacement after age 60, and for patients 60 and under it leaves the decision to the regional contractor CMS 2007. Our office checks this before we set a date. Fourth, we decide together: replacement, fusion, or more time without surgery. Bring your questions.

    Refs: CMS, Medicare Coverage Database, 2007
  14. The studies behind this talk

    1.Blumenthal S, McAfee PC, Guyer RD, Hochschuler SH, Geisler FH, Holt RT. A prospective, randomized, multicenter Food and Drug Administration investigational device exemptions study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: part I: evaluation of clinical outcomes. Spine (Phila Pa 1976). 2005;30(14):1565-75; discussion E387-91.

    2.Guyer RD, McAfee PC, Banco RJ, Bitan FD, Cappuccino A, Geisler FH. Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: five-year follow-up. Spine J. 2009;9(5):374-86.

    3.Zigler J, Delamarter R, Spivak JM, Linovitz RJ, Danielson GO 3rd, Haider TT. Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease. Spine (Phila Pa 1976). 2007;32(11):1155-62; discussion 1163.

    4.Zigler JE, Delamarter RB. Five-year results of the prospective, randomized, multicenter, Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential arthrodesis for the treatment of single-level degenerative disc disease. J Neurosurg Spine. 2012;17(6):493-501.

    5.Garcia R Jr, Yue JJ, Blumenthal S, Coric D, Patel VV, Leary SP. Lumbar Total Disc Replacement for Discogenic Low Back Pain: Two-year Outcomes of the activL Multicenter Randomized Controlled IDE Clinical Trial. Spine (Phila Pa 1976). 2015;40(24):1873-81.

    6.Furunes H, Storheim K, Brox JI, Johnsen LG, Skouen JS, Franssen E. Total disc replacement versus multidisciplinary rehabilitation in patients with chronic low back pain and degenerative discs: 8-year follow-up of a randomized controlled multicenter trial. Spine J. 2017;17(10):1480-1488.

    7.Furunes H, Hellum C, Espeland A, Brox JI, Småstuen MC, Berg L. Adjacent Disc Degeneration After Lumbar Total Disc Replacement or Nonoperative Treatment: A Randomized Study with 8-year Follow-up. Spine (Phila Pa 1976). 2018;43(24):1695-1703.

    8.Lemaire JP, Carrier H, Sariali el-H, Skalli W, Lavaste F. Clinical and radiological outcomes with the Charité artificial disc: a 10-year minimum follow-up. J Spinal Disord Tech. 2005;18(4):353-9.

    9.David T. Long-term results of one-level lumbar arthroplasty: minimum 10-year follow-up of the CHARITE artificial disc in 106 patients. Spine (Phila Pa 1976). 2007;32(6):661-6.

    10.Park SJ, Lee CS, Chung SS, Lee KH, Kim WS, Lee JY. Long-Term Outcomes Following Lumbar Total Disc Replacement Using ProDisc-II: Average 10-Year Follow-Up at a Single Institute. Spine (Phila Pa 1976). 2016;41(11):971-977.

    11.Laugesen LA, Paulsen RT, Carreon L, Ernst C, Andersen MØ. Patient-reported Outcomes and Revision Rates at a Mean Follow-up of 10 Years After Lumbar Total Disc Replacement. Spine (Phila Pa 1976). 2017;42(21):1657-1663.

    12.Lu S, Sun S, Kong C, Sun W, Hu H, Wang Q. Long-term clinical results following Charite III lumbar total disc replacement. Spine J. 2018;18(6):917-925.

    13.Guyer RD, Blumenthal SL, Shellock JL, Zigler JE, Ohnmeiss DD. Lumbar Total Disk Replacement Device Removals and Revisions Performed During a 20-Year Experience with 2141 Patients. Spine (Phila Pa 1976). 2024;49(10):671-676.

    14.Zigler JE, Glenn J, Delamarter RB. Five-year adjacent-level degenerative changes in patients with single-level disease treated using lumbar total disc replacement with ProDisc-L versus circumferential fusion. J Neurosurg Spine. 2012;17(6):504-11.

    15.Rainey S, Blumenthal SL, Zigler JE, Guyer RD, Ohnmeiss DD. Analysis of adjacent segment reoperation after lumbar total disc replacement. Int J Spine Surg. 2012;6:140-4.

    16.Harrop JS, Youssef JA, Maltenfort M, Vorwald P, Jabbour P, Bono CM. Lumbar adjacent segment degeneration and disease after arthrodesis and total disc arthroplasty. Spine (Phila Pa 1976). 2008;33(15):1701-7.

    17.Zigler J, Gornet MF, Ferko N, Cameron C, Schranck FW, Patel L. Comparison of Lumbar Total Disc Replacement With Surgical Spinal Fusion for the Treatment of Single-Level Degenerative Disc Disease: A Meta-Analysis of 5-Year Outcomes From Randomized Controlled Trials. Global Spine J. 2018;8(4):413-423.

    18.Patel S, Mendonca A, Nischal SA, Kale KM, Hines K, Heller J. Total disc replacement versus lumbar interbody fusion for degenerative disc disease: a meta-analysis of randomized controlled trials. Neurosurg Focus. 2026;61(1):E11.

    19.Wen DJ, Tavakoli J, Tipper JL. Lumbar Total Disc Replacements for Degenerative Disc Disease: A Systematic Review of Outcomes With a Minimum of 5 years Follow-Up. Global Spine J. 2024;14(6):1827-1837.

    20.Kurtz SM, van Ooij A, Ross R, de Waal Malefijt J, Peloza J, Ciccarelli L. Polyethylene wear and rim fracture in total disc arthroplasty. Spine J. 2007;7(1):12-21.

    21.Punt IM, Austen S, Cleutjens JP, Kurtz SM, ten Broeke RH, van Rhijn LW. Are periprosthetic tissue reactions observed after revision of total disc replacement comparable to the reactions observed after total hip or knee revision surgery?. Spine (Phila Pa 1976). 2012;37(2):150-9.

    22.Lindley EM, McBeth ZL, Henry SE, Cooley R, Burger EL, Cain CM. Retrograde ejaculation after anterior lumbar spine surgery. Spine (Phila Pa 1976). 2012;37(20):1785-9.

    23.Ahn J, Courtois EC, Ohnmeiss DD. Impact of Age on the Occurrence of Vascular Complications in Patients Undergoing Anterior Lumbar Approach Surgery. Spine (Phila Pa 1976). 2024;49(20):E327-E330.

    24.Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet. 2019;393(10172):655-663.

    25.Sharkey PF, Lichstein PM, Shen C, Tokarski AT, Parvizi J. Why are total knee arthroplasties failing today--has anything changed after 10 years?. J Arthroplasty. 2014;29(9):1774-8.

    26.CMS. National Coverage Determination 150.10: Lumbar Artificial Disc Replacement (LADR). Medicare Coverage Database. 2007.

    27.Sköld C, Tropp H, Berg S. Five-year follow-up of total disc replacement compared to fusion: a randomized controlled trial. Eur Spine J. 2013;22(10):2288-95.

    28.Berg S, Tullberg T, Branth B, Olerud C, Tropp H. Total disc replacement compared to lumbar fusion: a randomised controlled trial with 2-year follow-up. Eur Spine J. 2009;18(10):1512-9.

    29.Siepe CJ, Wiechert K, Khattab MF, Korge A, Mayer HM. Total lumbar disc replacement in athletes: clinical results, return to sport and athletic performance. Eur Spine J. 2007;16(7):1001-13.

    30.Radcliff K, Zigler J, Braxton E, Buttermann G, Coric D, Derman P. Final Long-Term Reporting from a Randomized Controlled IDE Trial for Lumbar Artificial Discs in Single-Level Degenerative Disc Disease: 7-Year Results. Int J Spine Surg. 2021;15(4):612-632.

    31.Upfill-Brown A, Policht J, Sperry BP, Ghosh D, Shah AA, Sheppard WL, et al.. National trends in the utilization of lumbar disc replacement for lumbar degenerative disc disease over a 10-year period, 2010 to 2019. J Spine Surg. 2022;8(3):343-352.

    32.Khalid SI, Deysher D, Thompson K, Ostrov PB, Hossa J, Mirpuri P, et al.. Outcomes of patients undergoing single-level arthroplasty versus anterior lumbar interbody fusion. Acta Neurochir (Wien). 2023;165(7):1915-1921.

    33.Vanaclocha V, Jordá-Gómez P, Saiz-Sapena N, Martínez-Leon J, Vanaclocha L. Long-term outcomes of total lumbar disc prosthesis: Sustained pain relief. N Am Spine Soc J. 2025;24:100813.

    34.Carlson J, Giblin M. Long-Term Results of Charité Lumbar Disc Replacement: A 17-Year Follow-Up in a Workers' Compensation Cohort. Int J Spine Surg. 2022;16(5):831-836.

    35.Fritzell P, Berg S, Borgström F, Tullberg T, Tropp H. Cost effectiveness of disc prosthesis versus lumbar fusion in patients with chronic low back pain: randomized controlled trial with 2-year follow-up. Eur Spine J. 2011;20(7):1001-11.

    36.Guyer RD, Pettine K, Roh JS, Dimmig TA, Coric D, McAfee PC, et al.. Five-Year Follow-Up of a Prospective, Randomized Trial Comparing Two Lumbar Total Disc Replacements. Spine (Phila Pa 1976). 2016;41(1):3-8.

    37.Narendran N, Mikhail CM, Nilssen PK, Tuchman A, Skaggs DL. Lumbar Total Disc Replacement Leads to Increased Subsequent Facet Injections Compared to Anterolateral Lumbar Interbody Fusions. Global Spine J. 2025;15(3):1733-1742.

    38.Shukla GG, Wu A, Matur AV, McGrath K, Khalid S, Garner R, et al.. Lumbar Arthroplasty Is Associated With a Lower Incidence of Adjacent Segment Disease Compared With ALIF: A Propensity-matched Analysis. Spine (Phila Pa 1976). 2023;48(14):978-983.

    39.FDA. Summary of Safety and Effectiveness Data: prodisc L Total Disc Replacement (PMA P050010 and two-level supplement S020). US Food and Drug Administration. 2020.

    40.FDA. Summary of Safety and Effectiveness Data: activL Artificial Disc (PMA P120024). US Food and Drug Administration. 2015.

    41.Aetna. Clinical Policy Bulletin 0591: Intervertebral Disc Prostheses. Aetna Clinical Policy Bulletins. 2026.

    42.Cigna, EviCore. CMM-610: Lumbar Total Disc Arthroplasty, V1.0.2026. Cigna Medical Coverage Policies: Musculoskeletal (EviCore). 2026.

    43.Carelon. Clinical Appropriateness Guidelines: Spine Surgery, Lumbar Disc Arthroplasty section (MSK03-0926.1). Carelon Medical Benefits Management. 2026.

    44.UnitedHealthcare. Medical Policy 2026T0437PP: Total Artificial Disc Replacement for the Spine. UnitedHealthcare. 2026.

    45.Horizon. Medical Policy (Surgery) #051: Artificial Intervertebral Disc, Lumbar Spine. Horizon Blue Cross Blue Shield of New Jersey. 2020.

    Full reference list with DOI and PubMed links is available in the online references view.

    Your decision
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    These are the studies the numbers came from. Every one was checked on PubMed in October 2026. The reference page of this deck has the full list with links.

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    Scan for these slides, the plain-language notes, and every study with a link. A PowerPoint version is at talks.aaronweymd.com/downloads/lumbar-disc-replacement-patient-talk.pptx

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